PTCB Updated PTCE Exam Questions and Answers by alaia

Comprehensive and Detailed Step-by-Step Explanation:

Mycophenolateis animmunosuppressantused inorgan transplantsand isteratogenic (causes birth defects).It requiresRisk Evaluation and Mitigation Strategies (REMS).

????Explanation of Answer Choices:✅B. Mycophenolate→Correct.High risk ofbirth defects, requiring REMS.❌A. Miconazole→ Incorrect.An antifungal with no REMS requirement.❌C. Phentermine→ Incorrect.Used for weight loss, not teratogenic.❌D. Phenytoin→ Incorrect.Has risks but no REMS requirement.

????Reference:

FDA REMS Program for Mycophenolate

PTCB Exam: Medication Safety & REMS

Comprehensive and Detailed Step-by-Step Explanation:

TheNational Drug Code (NDC)is a10- or 11-digit numberidentifying a drug'smanufacturer, product, and package size.

????NDC Format:

XXXXX−YYYY−ZZ\text{XXXXX} - \text{YYYY} - \text{ZZ}XXXXX−YYYY−ZZ

First 5 digits= Manufacturer

Middle 4 digits= Drug, strength, and formulation

Last 2 digits=Package size

✅A. Package size→Correct.Since the first two segments(00781-1506)are identical, the difference is in thelast segment, which representspackage size.❌B. Dosage→ Incorrect. Thedosage (mg strength) remains the same.❌C. Manufacturer→ Incorrect. Themanufacturer is the same (first 5 digits are identical).❌D. Strength→ Incorrect. Thestrength is unchanged.

????Reference:

FDA NDC Directory

PTCB Inventory Management Guidelines

Comprehensive and Detailed Step-by-Step Explanation:

Hospitals mayredispenseunopened, sealed, unit-dose medicationsreturned frominpatients, as long as they areproperly storedand not tampered with.

????Explanation of Answer Choices:✅C. Unopened units-of-use returned from inpatients may be redispensed→Correct.Hospital pharmacies canredispense sealed unit-dose medications from inpatients.❌A. Unlabeled medications may be dispensed by the nurse at discharge→ Incorrect.Unlabeled meds cannot be dispensed due to safety concerns.❌B. Unopened units-of-use returned from outpatients may be redispensed→ Incorrect.Medications dispensed to outpatients cannot be returned to stock.❌D. Crediting of unused doses is not feasible→ Incorrect.Many hospitals have systems for crediting unused doses.

????Reference:

USP <795> and <797>: Hospital Medication Storage

PTCB Medication Safety Regulations

Lorazepam oral concentrate is a high-potency liquid formulation often dispensed in 2 mg/mL. Due to its strength and risk of dosing errors, it must be dispensed with a calibrated oral syringe for accurate dosing, especially in pediatric or geriatric patients.

From Pharmacy Technician Certification Exam Review:

“Concentrated oral liquids should always be dispensed with calibrated measuring devices to prevent overdose or underdose.”

Other options:

Enoxaparin – subcutaneous injection

Albuterol/ipratropium – inhalation

Polyethylene glycol 3350 – powder mixed with water (no syringe required)